Thursday 31 December 2009

Pronoran




Pronoran may be available in the countries listed below.


Ingredient matches for Pronoran



Piribedil

Piribedil is reported as an ingredient of Pronoran in the following countries:


  • Georgia

  • Latvia

  • Lithuania

  • Poland

  • Romania

  • Russian Federation

International Drug Name Search

Friday 25 December 2009

Codethyline




Codethyline may be available in the countries listed below.


Ingredient matches for Codethyline



Ethylmorphine

Ethylmorphine hydrochloride (a derivative of Ethylmorphine) is reported as an ingredient of Codethyline in the following countries:


  • Belgium

International Drug Name Search

Monday 21 December 2009

Sertralin Krka




Sertralin Krka may be available in the countries listed below.


Ingredient matches for Sertralin Krka



Sertraline

Sertraline hydrochloride (a derivative of Sertraline) is reported as an ingredient of Sertralin Krka in the following countries:


  • Denmark

  • Finland

  • Sweden

International Drug Name Search

Thursday 10 December 2009

Chlordiazepoxide




In the US, Chlordiazepoxide (chlordiazepoxide systemic) is a member of the drug class benzodiazepines and is used to treat Alcohol Withdrawal, Anxiety, Burning Mouth Syndrome and Light Sedation.

US matches:

  • Chlordiazepoxide

  • Chlordiazepoxide Injection

  • Chlordiazepoxide/Clidinium

  • Chlordiazepoxide/Methscopolamine

  • Chlordiazepoxide and clidinium

  • Chlordiazepoxide and amitriptyline

  • Chlordiazepoxide hydrochloride

  • Chlordiazepoxide Capsules

  • Chlordiazepoxide,Amitriptyline

  • Chlordiazepoxide/Amitriptyline

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

N05BA02

CAS registry number (Chemical Abstracts Service)

0000058-25-3

Chemical Formula

C16-H14-Cl-N3-O

Molecular Weight

299

Therapeutic Categories

Anxiolytic agent

Benzodiazepine derivative

Agent for premedication

Muscle relaxant

Treatment of alcohol withdrawal symptoms

Chemical Name

3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide

Foreign Names

  • Chlordiazepoxidum (Latin)
  • Chlordiazepoxid (German)
  • Chlordiazépoxide (French)
  • Clordiazepoxido (Spanish)

Generic Names

  • Chlordiazepoxide (OS: JAN, BAN)
  • Chlordiazépoxide (OS: DCF)
  • Clordiazepossido (OS: DCIT)
  • Diazefonate (IS)
  • Dizepin (IS)
  • Droxol (IS)
  • Metaminodiazepoxide (IS)
  • Chlordiazepoxid (PH: Ph. Eur. 6)
  • Chlordiazepoxide (PH: BP 2010, JP XV, USP 32, Ph. Eur. 6)
  • Chlordiazépoxide (PH: Ph. Eur. 6)
  • Chlordiazepoxidum (PH: Ph. Eur. 6)
  • Chlordiazepoxide Hydrochloride (OS: JAN, USAN, BANM)
  • CDP 10 (IS)
  • NSC 115748 (IS)
  • Ro 5-0690 (IS)
  • Chlordiazépoxide (chlorhydrate de) (PH: Ph. Eur. 6)
  • Chlordiazepoxide Hydrochloride (PH: BP 2010, USP 32, Ph. Eur. 6)
  • Chlordiazepoxidhydrochlorid (PH: Ph. Eur. 6)
  • Chlordiazepoxidi hydrochloridum (PH: Ph. Eur. 6)

Brand Names

  • Amixide (Chlordiazepoxide and Amitriptyline)
    Sun, Russian Federation


  • Apo-Chlorax (Chlordiazepoxide and Clidinium Bromide)
    Apotex, Singapore


  • Balance
    Astellas, Japan


  • Braxidin (Chlordiazepoxide and Clidinium)
    Sanbe, Indonesia


  • Chloordiazepoxide Actavis
    Actavis, Netherlands


  • Chloordiazepoxide CF
    Centrafarm, Netherlands


  • Chloordiazepoxide FLX
    Accord Healthcare, Netherlands


  • Chloordiazepoxide PCH
    Pharmachemie, Netherlands


  • Chloordiazepoxide ratiopharm
    ratiopharm, Netherlands


  • Chloordiazepoxide Sandoz
    Sandoz, Netherlands


  • Chlordiazepoxide and Amitriptyline hydrochloride (Chlordiazepoxide and Amitriptyline)
    Mylan, United States


  • Chlordiazepoxide Yimin Pharm
    Yimin, China


  • Cliad (Chlordiazepoxide and Clidinium)
    Interbat, Indonesia


  • Clordiazepoxido L.CH.
    Chile, Chile


  • Consun
    Tsuruhara Seiyaku, Japan


  • Contol
    Takeda, Japan


  • Defobin
    Zentiva, Czech Republic


  • Elenium
    Polfa, Czech Republic; Polfa Tarchomin, Georgia; Polfa Tarchomin, Latvia; Polfa Tarchomin, Poland; Polfa Tarchomin, Russian Federation; Polfa Tarchomin S. A., Hungary; Tarchomin, Bulgaria; Tarchominskie, Lithuania; WZF Polfa, Slovakia


  • Epirax
    Eipico Egyptian International Pharmaceutical Industries CO, Ethiopia


  • Equilibrium
    Jagson Pal, India


  • Iremal
    Remedica, Cyprus


  • Kenspa (Chlordiazepoxide and Clidinium)
    Kenyaku, Thailand


  • Klidibrax (Chlordiazepoxide and Clidinium)
    Sandoz, Indonesia


  • Klopoxid Dak
    Nycomed, Denmark


  • Klordiazepoxid Actavis
    Actavis, Iceland


  • Librax (Chlordiazepoxide and Clidinium Bromide)
    Combiphar, Indonesia; ICN, Bahrain; ICN Iberica SA, Greece; ICN Switzerland, Oman; IFET, Greece; Meda, France; Pharmaco, South Africa; PL, Thailand; Valeant, Indonesia; Valeant, Italy; Valeant, Peru; Valeant Pharmaceuticals, Vietnam; Valeant Pharmaceuticals Switzerland GmbH, Switzerland


  • Librium
    Combiphar, Indonesia; ICN, Bahrain; Meda, Ireland; Nicholas, India; Pharmaco, South Africa; Teva, Hungary; Valeant, Germany; Valeant, Hong Kong; Valeant, Indonesia


  • Librocol (Chlordiazepoxide and Clidinium Bromide)
    Lagap, Switzerland


  • Limbitrol (Chlordiazepoxide and Amitriptyline)
    Meda, Switzerland; Pharmaco, South Africa; Valeant, United States


  • Limbitryl (Chlordiazepoxide and Amitriptyline)
    Valeant, Italy


  • Limbritol (Chlordiazepoxide and Amitriptyline)
    Combiphar, Indonesia; Valeant, Indonesia


  • Multum
    Rosen, Germany


  • Paxium
    Jaba, Portugal


  • Radepur
    AWD.pharma, Germany


  • Renagas (Chlordiazepoxide and Clidinium)
    Fahrenheit, Indonesia


  • Risachief
    Kyorin Rimedio, Japan


  • Risolid
    Actavis, Denmark; Actavis, Finland


  • Apo-Chlorax (Chlordiazepoxide and Clidinium Bromide)
    Apotex, Canada; Apotex, Vietnam


  • Apo-Chlordiazepoxide
    Apotex, Canada


  • Benpine
    Atlantic, Singapore


  • Chlordiazepoxide Hydrochloride
    Teva USA, United States; USL Pharma, United States; Watson, United States


  • Diapatol (Chlordiazepoxide and Amitriptyline)
    Teofarma, Italy


  • Huberplex
    Teofarma, Spain


  • Klorpo
    Beacons, Singapore


  • Librax (Chlordiazepoxide and Clidinium Bromide)
    Valeant, Canada


  • Librium
    Valeant, Italy; Valeant, Malta; Valeant, United States


  • Limbitrol (Chlordiazepoxide and Amitriptyline)
    Valeant, Austria


  • O.C.M.
    Gobbi, Argentina


  • Oasil
    Gap, Greece


  • Omnalio
    Estedi, Spain


  • Psico Blocan (Chlordiazepoxide and Scopolamine)
    Estedi, Spain


  • Psicosedin
    Farmasa, Brazil


  • Spasmium (Chlordiazepoxide and Alverine)
    Soho, Indonesia


  • Tumax (Chlordiazepoxide and Clidinium)
    Sriprasit, Thailand

International Drug Name Search

Glossary

BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Monday 7 December 2009

Xylocaine Injection




Xylocaine Injection may be available in the countries listed below.


Ingredient matches for Xylocaine Injection



Lidocaine

Lidocaine hydrochloride (a derivative of Lidocaine) is reported as an ingredient of Xylocaine Injection in the following countries:


  • Hong Kong

  • Singapore

International Drug Name Search

Sunday 6 December 2009

Romurtide




Scheme

Rec.INN

CAS registry number (Chemical Abstracts Service)

0078113-36-7

Chemical Formula

C43-H78-N6-O13

Molecular Weight

887

Therapeutic Category

Immunomodulator

Chemical Name

2-Acetamido-3-O-[(R)-1-[[(S)-1-[[(R)-1-carbamoyl-3-[[(S)-carboxy-5-stearamidopentyl]carbamoyl] propyl]carbamoyl]ethyl]carbamoyl]ethyl]-2-deoxy-D-glucopyranose

Foreign Names

  • Romurtidum (Latin)
  • Romurtid (German)
  • Romurtide (French)
  • Romurtida (Spanish)

Generic Names

  • Romurtide (OS: JAN)
  • DJ 7041 (IS: Daiichi)
  • MDP-Lys (IS: L18)
  • Muroctasin (IS)

Brand Name

  • Nopia
    Daiichi Sankyo, Japan

International Drug Name Search

Glossary

ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Pravastatin Pliva




Pravastatin Pliva may be available in the countries listed below.


Ingredient matches for Pravastatin Pliva



Pravastatin

Pravastatin sodium salt (a derivative of Pravastatin) is reported as an ingredient of Pravastatin Pliva in the following countries:


  • Czech Republic

  • Estonia

  • Hungary

  • Latvia

  • Lithuania

  • Slovenia

International Drug Name Search

Saturday 5 December 2009

Fusidate




Fusidate may be available in the countries listed below.


Ingredient matches for Fusidate



Fusidic Acid

Fusidic Acid sodium (a derivative of Fusidic Acid) is reported as an ingredient of Fusidate in the following countries:


  • Bangladesh

  • Sri Lanka

International Drug Name Search

Friday 4 December 2009

Oftimolo




Oftimolo may be available in the countries listed below.


Ingredient matches for Oftimolo



Timolol

Timolol maleate (a derivative of Timolol) is reported as an ingredient of Oftimolo in the following countries:


  • Italy

International Drug Name Search

Thursday 3 December 2009

Dermiplus-V




Dermiplus-V may be available in the countries listed below.


Ingredient matches for Dermiplus-V



Clotrimazole

Clotrimazole is reported as an ingredient of Dermiplus-V in the following countries:


  • Peru

International Drug Name Search

Wednesday 2 December 2009

Clamist




Clamist may be available in the countries listed below.


Ingredient matches for Clamist



Clemastine

Clemastine fumarate (a derivative of Clemastine) is reported as an ingredient of Clamist in the following countries:


  • India

International Drug Name Search

Friday 27 November 2009

Zolpidem Normon




Zolpidem Normon may be available in the countries listed below.


Ingredient matches for Zolpidem Normon



Zolpidem

Zolpidem is reported as an ingredient of Zolpidem Normon in the following countries:


  • Honduras

Zolpidem tartrate (a derivative of Zolpidem) is reported as an ingredient of Zolpidem Normon in the following countries:


  • Costa Rica

  • El Salvador

  • Guatemala

  • Nicaragua

  • Panama

  • Spain

International Drug Name Search

Wednesday 25 November 2009

Dantrium


Generic Name: dantrolene (oral) (DAN troe leen)

Brand Names: Dantrium


What is dantrolene?

Dantrolene is a muscle relaxant.


Dantrolene is used to treat muscle spasticity (stiffness and spasms) caused by conditions such as a spinal cord injury, stroke, cerebral palsy, or multiple sclerosis.


Dantrolene is also used to prevent muscle stiffness and spasms caused by malignant hyperthermia (a rapid rise in body temperature) that can occur during surgery with certain types of anesthesia.


Dantrolene may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about dantrolene?


You should not take this medication if you are allergic to dantrolene, or if you have liver disease such as hepatitis or cirrhosis. You may be more likely to develop liver problems while taking dantrolene if you are a woman, or if you are older than 35. Talk with your doctor about your individual risk. Do not use dantrolene at a time when muscle tone is needed to assure safe balance and movement for certain activities. In some situations, it may endanger your physical safety to be in a state of reduced muscle tone.

Before taking dantrolene, tell your doctor if you have a history of liver disease, a breathing disorder such as COPD, heart disease, or a history of heart attack.


Dantrolene can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Dantrolene can cause muscle weakness, which can affect your ability to swallow. Use caution to prevent choking while you are eating meals. Talk with your doctor if you are unable to eat because of this side effect. Avoid drinking alcohol. It can increase some of the side effects of dantrolene.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.


What should I discuss with my healthcare provider before taking dantrolene?


You should not take this medication if you are allergic to dantrolene, or if you have liver disease such as hepatitis or cirrhosis. You may be more likely to develop liver problems while taking dantrolene if you are a woman, or if you are older than 35. Talk with your doctor about your individual risk.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:



  • a history of liver disease;




  • a breathing disorder such as COPD (chronic obstructive pulmonary disease); or




  • heart disease, or a history of heart attack.




FDA pregnancy category C. It is not known whether dantrolene is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Dantrolene can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Dantrolene should not be given to a child younger than 5 years old.

How should I take dantrolene?


Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.


Your doctor may occasionally change your dose to make sure you get the best results from this medication.


Take this medicine with a full glass of water. If you take dantrolene within 4 hours before surgery, use only enough water needed to swallow the pill. Dantrolene can cause muscle weakness, which can affect your ability to swallow. Use caution to prevent choking while you are eating meals. Talk with your doctor if you are unable to eat because of this side effect. Store dantrolene at room temperature away from moisture and heat.

See also: Dantrium dosage (in more detail)

What happens if I miss a dose?


Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include vomiting, diarrhea, and extreme drowsiness or muscle weakness.


What should I avoid while taking dantrolene?


Do not use dantrolene at a time when muscle tone is needed to assure safe balance and movement for certain activities. In some situations, it may endanger your physical safety to be in a state of reduced muscle tone. Dantrolene can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of dantrolene. Avoid exposure to sunlight, sunlamps, or tanning beds. Dantrolene can make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use sunscreen (SPF 15 or higher) when you are outdoors.

Dantrolene side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • severe diarrhea or constipation;




  • weak or shallow breathing;




  • pale skin, easy bruising or bleeding;




  • trouble swallowing, especially if it causes choking;




  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);




  • black, bloody, or tarry stools;




  • coughing up blood or vomit that looks like coffee grounds;




  • seizure (black-out or convulsions); or




  • urinating less than usual or not at all.



Less serious side effects may include:



  • drowsiness, dizziness, weakness, tired feeling;




  • mild diarrhea or constipation;




  • mild nausea, vomiting, stomach pain;




  • problems with speech, balance, or walking;




  • headache, confusion, vision problems;




  • sleep problems (insomnia);




  • sweating, drooling; or




  • urinating more than usual.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect dantrolene?


Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, and medicine for seizures, depression or anxiety can add to sleepiness caused by dantrolene. Tell your doctor if you regularly use any of these medicines, or any other muscle relaxers.

Tell your doctor about all other medications you use, especially:



  • birth control pills and other hormones; or




  • a heart or blood pressure medication such as amlodipine (Norvasc), diltiazem (Tiazac, Cartia, Cardizem), felodipine (Plendil), nicardipine (Cardene), nifedipine (Procardia, Adalat), nimodipine (Nimotop), nisoldipine (Sular), or verapamil (Calan, Covera, Isoptin, Verelan).



This list is not complete and there may be other drugs that can interact with dantrolene. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More Dantrium resources


  • Dantrium Side Effects (in more detail)
  • Dantrium Dosage
  • Dantrium Use in Pregnancy & Breastfeeding
  • Drug Images
  • Dantrium Drug Interactions
  • Dantrium Support Group
  • 2 Reviews for Dantrium - Add your own review/rating


  • Dantrium Prescribing Information (FDA)

  • Dantrium MedFacts Consumer Leaflet (Wolters Kluwer)

  • Dantrium Monograph (AHFS DI)

  • Dantrium Advanced Consumer (Micromedex) - Includes Dosage Information

  • Dantrolene Prescribing Information (FDA)

  • Dantrium Intravenous Prescribing Information (FDA)

  • Dantrium Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information



Compare Dantrium with other medications


  • Malignant Hyperthermia
  • Spasticity


Where can I get more information?


  • Your pharmacist can provide more information about dantrolene.

See also: Dantrium side effects (in more detail)


Monday 23 November 2009

Dexalgen




Dexalgen may be available in the countries listed below.


Ingredient matches for Dexalgen



Hydroxocobalamin

Hydroxocobalamin is reported as an ingredient of Dexalgen in the following countries:


  • Brazil

International Drug Name Search

Saturday 21 November 2009

Tetraguard




Tetraguard may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Tetraguard



Oxytetracycline

Oxytetracycline magnesiumoxyethylammonium (a derivative of Oxytetracycline) is reported as an ingredient of Tetraguard in the following countries:


  • New Zealand

International Drug Name Search

Wednesday 18 November 2009

Risperidona Asol




Risperidona Asol may be available in the countries listed below.


Ingredient matches for Risperidona Asol



Risperidone

Risperidone is reported as an ingredient of Risperidona Asol in the following countries:


  • Spain

International Drug Name Search

Tuesday 17 November 2009

rivastigmine transdermal


Generic Name: rivastigmine transdermal (riv a STIG meen)

Brand Names: Exelon


What is rivastigmine transdermal?

Rivastigmine improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical called acetylcholine (ah see til KO leen). People with dementia usually have lower levels of this chemical, which is important for the processes of memory, thinking, and reasoning.


Rivastigmine transdermal (skin patch) is used to treat mild to moderate dementia caused by Alzheimer's or Parkinson's disease.


Rivastigmine transdermal may also be used for purposes not listed in this medication guide.


What is the most important information I should know about rivastigmine transdermal?


You should not use rivastigmine if you are allergic to it.

Before using rivastigmine transdermal, tell your doctor if you have liver disease, a heart rhythm disorder such as "sick sinus syndrome" (slow heartbeats), an enlarged prostate, urination problems, a seizure disorder, asthma or allergies, tremors or uncontrolled muscle movements, or a history of stomach ulcer.


Always remove an old patch before putting on a new one. Do not wear more than 1 patch at a time. Stop using rivastigmine transdermal and call your doctor at once if the medicine causes you to have nausea and vomiting, loss of appetite, or weight loss.

If you stop using rivastigmine transdermal for any reason, do not restart the medication without talking to your doctor first. You may need to restart treatment with a lower dose.


If you need surgery, tell the surgeon ahead of time that you are using rivastigmine transdermal.


Rivastigmine transdermal may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What should I discuss with my healthcare provider before using rivastigmine transdermal?


You should not use rivastigmine if you are allergic to it.

To make sure you can safely use rivastigmine transdermal, tell your doctor if you have any of these other conditions:



  • liver disease;




  • recent weight loss or lack of appetite;




  • a heart rhythm disorder such as "sick sinus syndrome" (slow heartbeats);




  • a history of stomach ulcer;




  • an enlarged prostate or urination problems;




  • epilepsy or other seizure disorder;




  • asthma or any allergies; or




  • tremors (dyskinesia) or uncontrolled muscle movements.




FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether rivastigmine transdermal passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use rivastigmine transdermal?


Use exactly as prescribed by your doctor. Do not apply more patches or use them for longer than recommended. Follow the directions on your prescription label.


This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.


Never cut or tear a rivastigmine patch.

Apply the skin patch to a flat, hairless area of the chest, back, side, or outer side of your upper arm. Press the patch firmly with the palm making sure it sticks firmly, especially around the edges.


Avoid placing the patch where it will be rubbed by tight clothing, or in the folds of your skin. The patch should remain flat on the skin at all times. Take care to avoid accidentally removing the patch while showering or during physical activity.


You will wear the patch for 24 hours and then remove it and put on a new one. Apply the new patch to a different skin area on your back each day. Do not use the same spot again for at least 14 days.


Always remove an old patch before putting on a new one. Do not wear more than 1 patch at a time.

If a patch falls off, apply a new patch and wear it for the rest of the day. Change the patch at your usual time the next day.


After removing a skin patch fold it in half, sticky side in, and throw it away where children and pets cannot get to it.


Always wash your hands after removing the patch.

If you need surgery, tell the surgeon ahead of time that you are using rivastigmine transdermal. You may need to stop using the medicine for a short time.


It may take up to 4 weeks of using this medicine before your symptoms improve. For best results, keep using the patches as directed.


If you stop using rivastigmine transdermal for any reason, do not restart the medication without talking to your doctor first. You may need to restart treatment with a lower dose.


Store at room temperature away from moisture and heat. Keep each patch in its foil pouch until you are ready to use it.

What happens if I miss a dose?


Apply a skin patch as soon as you remember. Or you may wait until the next day to apply a patch and skip the missed dose. Do not use extra patches to make up the missed dose.


If you miss several doses in a row, call your doctor before using any more of this medication.

What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe nausea, vomiting, diarrhea, slow heartbeat, slow or shallow breathing, or hallucinations.


What should I avoid while using rivastigmine transdermal?


Do not use any cream, lotion, ointment, oil, or powder on the skin where you plan to apply a skin patch. The patch may not stick well to the skin.


Avoid applying heat to the skin where the patch is worn, because it may increase the amount of medicine your body absorbs. Heat sources include hot tubs, heating pads, heat lamps, saunas, heated water beds, and direct sunlight. Rivastigmine transdermal may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Rivastigmine transdermal side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using rivastigmine transdermal and call your doctor at once if you have a serious side effect such as:

  • nausea and vomiting, loss of appetite, weight loss;




  • black or bloody stools, coughing up blood or vomit that looks like blood or coffee grounds;




  • restless muscle movements in your eyes, tongue, jaw, or neck, tremor (uncontrolled shaking);




  • sudden numbness or weakness, headache, confusion, problems with vision, speech, or balance;




  • pale skin, easy bruising or bleeding;




  • confusion, hallucinations; or




  • pain or burning when you urinate.



Less serious side effects may include:



  • diarrhea, stomach pain;




  • headache, tired feeling;




  • anxiety, depressed mood;




  • redness, itching, or swelling where the patch was worn;




  • dizziness, spinning feeling; or




  • sleep problems (insomnia).



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Rivastigmine transdermal Dosing Information


Usual Adult Dose for Alzheimer's Disease:

Initial Oral Dose: 1.5 mg orally twice a day with morning and evening meals.

After a minimum of two weeks of treatment, if the initial dosage is well tolerated, it may be increased to 3 mg twice a day. Subsequent increases to 4.5 mg and 6 mg twice a day should be attempted only after a minimum of 2 weeks at the previous dosage. The dosage of rivastigmine shown to be effective in controlled clinical trials is 3 to 6 mg twice a day. There is evidence from the clinical trials that dosages at the higher end of this range may be more beneficial.

Initial Patch Dose: 4.6 mg/24 hours

After a minimum of four weeks of treatment and if well tolerated, the dose of the patch be increased to 9.5 mg/24 hours, which is the recommended effective dose.

Maintenance Patch Dose: Dose increases should occur only after a minimum of four weeks at the previous dose, and only if the previous dose has been well tolerated. The maximum recommended dose is 9.5 mg/ 24 hours. Higher doses confer no appreciable additional benefit, and are associated with significant increase in the incidence of adverse events.

Switching from Capsules or Oral Solution: Patients treated with capsules or oral solution may be switched to patches as follows:
A patient who is on a total daily dose of less than 6 mg of oral rivastigmine can be switched to patch dose of 4.6 mg/24 hours.
A patient who is on a total daily dose of 6 to 12 mg of oral rivastigmine may be directly switched to a patch dose of 9.5 mg/24 hours.
It is recommended to apply the first patch on the day following the last oral dose.

Usual Adult Dose for Parkinson's Disease:

Initial dose: 1.5 mg orally twice a day with morning and evening meals

Subsequently, the dose may be increased to 3 mg orally twice a day and further to 4.5 mg twice a day and 6 mg twice a day (based on tolerability) with a minimum of 4 weeks at each dose.

Initial Patch Dose: 4.6 mg/24 hours

After a minimum of four weeks of treatment and if well tolerated, the dose of the patch be increased to 9.5 mg/24 hours, which is the recommended effective dose.

Maintenance Patch Dose: Dose increases should occur only after a minimum of four weeks at the previous dose, and only if the previous dose has been well tolerated. The maximum recommended dose is 9.5 mg/ 24 hours. Higher doses confer no appreciable additional benefit, and are associated with significant increase in the incidence of adverse events.

Switching from Capsules or Oral Solution: Patients treated with capsules or oral solution may be switched to patches as follows:
A patient who is on a total daily dose of less than 6 mg of oral rivastigmine can be switched to patch dose of 4.6 mg/24 hours.
A patient who is on a total daily dose of 6 to 12 mg of oral rivastigmine may be directly switched to a patch dose of 9.5 mg/24 hours.
It is recommended to apply the first patch on the day following the last oral dose.


What other drugs will affect rivastigmine transdermal?


Do not take rivastigmine capsules or oral liquid at the same time you are wearing the skin patch.

The following drugs can interact with rivastigmine transdermal. Tell your doctor if you are using any of these:



  • atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);




  • bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);




  • glycopyrrolate (Robinul);




  • mepenzolate (Cantil);




  • bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);




  • irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine);




  • aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), meloxicam (Mobic), and others; or




  • medicines used to treat Parkinson's Disease such as levodopa (Dopar, Larodopa, Sinemet, Atamet, others), bromocriptine (Parlodel, others), pergolide (Permax), pramipexole (Mirapex), or ropinirole (Requip).



This list is not complete and other drugs may interact with rivastigmine transdermal. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More rivastigmine transdermal resources


  • Rivastigmine transdermal Side Effects (in more detail)
  • Rivastigmine transdermal Dosage
  • Rivastigmine transdermal Use in Pregnancy & Breastfeeding
  • Rivastigmine transdermal Drug Interactions
  • Rivastigmine transdermal Support Group
  • 6 Reviews for Rivastigmine - Add your own review/rating


Compare rivastigmine transdermal with other medications


  • Alzheimer's Disease
  • Parkinson's Disease


Where can I get more information?


  • Your pharmacist can provide more information about rivastigmine transdermal.

See also: rivastigmine side effects (in more detail)


Monday 16 November 2009

Crezyme




Crezyme may be available in the countries listed below.


Ingredient matches for Crezyme



Pancreatin

Pancreatin is reported as an ingredient of Crezyme in the following countries:


  • Bangladesh

International Drug Name Search

Sunday 15 November 2009

Allantoin




Scheme

USAN

CAS registry number (Chemical Abstracts Service)

0000097-59-6

Chemical Formula

C4-H6-N4-O3

Molecular Weight

158

Therapeutic Categories

Wound healing agent

Dermatological agent: Antipsoriatic

Chemical Name

Urea, (2,5-dioxo-4-imidazolidinyl)-

Foreign Names

  • Allantoinum (Latin)
  • Allantoin (German)
  • Allantoïne (French)
  • Alantoína (Spanish)

Generic Names

  • Allantoin (OS: BAN, USAN)
  • Allantoïne (OS: DCF)
  • Cordianine (IS)
  • Allantoin (PH: BP 2010, USP 32, Ph. Eur. 6)
  • Allantoine (PH: Ph. Eur. 6)
  • Allantoinum (PH: Ph. Eur. 6)

Brand Names

  • Alantan
    Unia, Poland


  • Alantan-Plus (Allantoin and Dexpanthenol)
    Unia, Poland


  • Alphosyl
    Intra, Ireland


  • Contractubex (Allantoin and Heparin)
    Merz, Switzerland; Merz, Slovakia


  • Jox (Allantoin and Povidone-Iodine)
    Ivax, Slovakia


  • Masse Cream
    Ethnor, India


  • Polaramine Topico (Allantoin and Dexchlorpheniramine)
    Schering-Plough, Spain


  • Xerand
    Loreal, Taiwan

International Drug Name Search

Glossary

BANBritish Approved Name
DCFDénomination Commune Française
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Sunday 8 November 2009

Cisplatine Merck




Cisplatine Merck may be available in the countries listed below.


Ingredient matches for Cisplatine Merck



Cisplatin

Cisplatin is reported as an ingredient of Cisplatine Merck in the following countries:


  • Tunisia

International Drug Name Search

Propiverin-HCl Stada




Propiverin-HCl Stada may be available in the countries listed below.


Ingredient matches for Propiverin-HCl Stada



Propiverine

Propiverine hydrochloride (a derivative of Propiverine) is reported as an ingredient of Propiverin-HCl Stada in the following countries:


  • Germany

International Drug Name Search

Saturday 7 November 2009

Prolift




Prolift may be available in the countries listed below.


Ingredient matches for Prolift



Reboxetine

Reboxetine is reported as an ingredient of Prolift in the following countries:


  • Chile

Reboxetine mesilate (a derivative of Reboxetine) is reported as an ingredient of Prolift in the following countries:


  • Brazil

International Drug Name Search

Roaccutane




Roaccutane may be available in the countries listed below.


UK matches:

  • Roaccutane 10mg Soft Capsules (SPC)
  • Roaccutane 20mg Soft Capsules (SPC)

Ingredient matches for Roaccutane



Isotretinoin

Isotretinoin is reported as an ingredient of Roaccutane in the following countries:


  • Algeria

  • Aruba

  • Australia

  • Bahrain

  • Bangladesh

  • Belgium

  • Bosnia & Herzegowina

  • Botswana

  • Brazil

  • Bulgaria

  • Chile

  • Croatia (Hrvatska)

  • Cuba

  • Cyprus

  • Czech Republic

  • Dominican Republic

  • Estonia

  • France

  • Georgia

  • Ghana

  • Greece

  • Hong Kong

  • Iceland

  • Iran

  • Ireland

  • Israel

  • Jamaica

  • Jordan

  • Kazakhstan

  • Kenya

  • Kuwait

  • Latvia

  • Lebanon

  • Lithuania

  • Luxembourg

  • Macedonia

  • Malawi

  • Malaysia

  • Malta

  • Mauritius

  • Mexico

  • Moldova

  • Morocco

  • Namibia

  • Netherlands

  • New Zealand

  • Nigeria

  • Norway

  • Oman

  • Pakistan

  • Peru

  • Philippines

  • Qatar

  • Romania

  • Russian Federation

  • Saudi Arabia

  • Serbia

  • Singapore

  • Slovakia

  • Slovenia

  • South Africa

  • Sri Lanka

  • Sudan

  • Taiwan

  • Tanzania

  • Thailand

  • Trinidad & Tobago

  • Turkey

  • Uganda

  • United Arab Emirates

  • United Kingdom

  • Uruguay

  • Zambia

  • Zimbabwe

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Thursday 5 November 2009

Shemol




Shemol may be available in the countries listed below.


Ingredient matches for Shemol



Timolol

Timolol maleate (a derivative of Timolol) is reported as an ingredient of Shemol in the following countries:


  • Mexico

International Drug Name Search

Sunday 1 November 2009

Asamax




Asamax may be available in the countries listed below.


Ingredient matches for Asamax



Mesalazine

Mesalazine is reported as an ingredient of Asamax in the following countries:


  • Italy

  • Poland

International Drug Name Search

By-Madol




By-Madol may be available in the countries listed below.


Ingredient matches for By-Madol



Tramadol

Tramadol hydrochloride (a derivative of Tramadol) is reported as an ingredient of By-Madol in the following countries:


  • Ireland

International Drug Name Search

Saturday 17 October 2009

Cancidas




In the US, Cancidas (caspofungin systemic) is a member of the drug class echinocandins and is used to treat Aspergillosis - Invasive, Candida Infections - Systemic, Esophageal Candidiasis and Febrile Neutropenia.

US matches:

  • Cancidas

UK matches:

  • CANCIDAS 50 mg (formerly Caspofungin MSD)
  • CANCIDAS 70 mg (formerly Caspofungin MSD)
  • CANCIDAS (formerly Caspofungin MSD) (SPC)

Ingredient matches for Cancidas



Caspofungin

Caspofungin is reported as an ingredient of Cancidas in the following countries:


  • Spain

  • Tunisia

Caspofungin diacetate (a derivative of Caspofungin) is reported as an ingredient of Cancidas in the following countries:


  • Algeria

  • Argentina

  • Aruba

  • Australia

  • Austria

  • Bahamas

  • Barbados

  • Belgium

  • Belize

  • Bosnia & Herzegowina

  • Brazil

  • Canada

  • Cayman Islands

  • Chile

  • China

  • Colombia

  • Croatia (Hrvatska)

  • Czech Republic

  • Denmark

  • Dominican Republic

  • Ecuador

  • Finland

  • France

  • Germany

  • Greece

  • Hong Kong

  • Hungary

  • Iceland

  • Ireland

  • Israel

  • Italy

  • Jamaica

  • Luxembourg

  • Malaysia

  • Mexico

  • Netherlands

  • Netherlands Antilles

  • New Zealand

  • Norway

  • Peru

  • Philippines

  • Romania

  • Russian Federation

  • Serbia

  • Singapore

  • Slovakia

  • Slovenia

  • South Africa

  • Sweden

  • Switzerland

  • Taiwan

  • Thailand

  • Trinidad & Tobago

  • Turkey

  • United Kingdom

  • United States

  • Venezuela

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Sunday 11 October 2009

Gliprex




Gliprex may be available in the countries listed below.


Ingredient matches for Gliprex



Glimepiride

Glimepiride is reported as an ingredient of Gliprex in the following countries:


  • Hungary

International Drug Name Search

Thursday 8 October 2009

Corectin




Corectin may be available in the countries listed below.


Ingredient matches for Corectin



Bisoprolol

Bisoprolol fumarate (a derivative of Bisoprolol) is reported as an ingredient of Corectin in the following countries:


  • Poland

International Drug Name Search

Sunday 4 October 2009

Calcio Levofolinato Fidia




Calcio Levofolinato Fidia may be available in the countries listed below.


Ingredient matches for Calcio Levofolinato Fidia



Calcium Levofolinate

Calcium Levofolinate pentahydrate (a derivative of Calcium Levofolinate) is reported as an ingredient of Calcio Levofolinato Fidia in the following countries:


  • Italy

International Drug Name Search

Norlopin




Norlopin may be available in the countries listed below.


Ingredient matches for Norlopin



Amlodipine

Amlodipine besilate (a derivative of Amlodipine) is reported as an ingredient of Norlopin in the following countries:


  • Turkey

International Drug Name Search

Thursday 1 October 2009

Campral




In the US, Campral (acamprosate systemic) is a member of the drug class drugs used in alcohol dependence and is used to treat Alcohol Dependence.

US matches:

  • Campral

UK matches:

  • Campral EC (SPC)

Ingredient matches for Campral



Acamprosate

Acamprosate is reported as an ingredient of Campral in the following countries:


  • Denmark

  • Norway

  • Slovakia

Acamprosate calcium salt (a derivative of Acamprosate) is reported as an ingredient of Campral in the following countries:


  • Argentina

  • Australia

  • Austria

  • Belgium

  • Brazil

  • Canada

  • Chile

  • Czech Republic

  • Germany

  • Hungary

  • Ireland

  • Luxembourg

  • Netherlands

  • Poland

  • Portugal

  • Spain

  • Sweden

  • Switzerland

  • Turkey

  • United Kingdom

  • United States

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Monday 28 September 2009

Onetrim




Onetrim may be available in the countries listed below.


Ingredient matches for Onetrim



Sulfamethoxazole

Sulfamethoxazole is reported as an ingredient of Onetrim in the following countries:


  • Philippines

Trimethoprim

Trimethoprim is reported as an ingredient of Onetrim in the following countries:


  • Philippines

International Drug Name Search

Thursday 24 September 2009

Guaphan




Guaphan may be available in the countries listed below.


Ingredient matches for Guaphan



Guaifenesin

Guaifenesin is reported as an ingredient of Guaphan in the following countries:


  • Oman

International Drug Name Search

Monday 21 September 2009

Raniprotect




Raniprotect may be available in the countries listed below.


Ingredient matches for Raniprotect



Ranitidine

Ranitidine hydrochloride (a derivative of Ranitidine) is reported as an ingredient of Raniprotect in the following countries:


  • Germany

International Drug Name Search

Sunday 20 September 2009

Zipéprol




Zipéprol may be available in the countries listed below.


Ingredient matches for Zipéprol



Zipeprol

Zipéprol (DCF) is also known as Zipeprol (Rec.INN)

International Drug Name Search

Glossary

DCFDénomination Commune Française
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Friday 18 September 2009

Premosan




Premosan may be available in the countries listed below.


Ingredient matches for Premosan



Metoclopramide

Metoclopramide hydrochloride (a derivative of Metoclopramide) is reported as an ingredient of Premosan in the following countries:


  • Oman

International Drug Name Search

Friday 11 September 2009

Finasterida Pharmakern




Finasterida Pharmakern may be available in the countries listed below.


Ingredient matches for Finasterida Pharmakern



Finasteride

Finasteride is reported as an ingredient of Finasterida Pharmakern in the following countries:


  • Spain

International Drug Name Search

Wednesday 9 September 2009

Calicumborogluconat




Calicumborogluconat may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Calicumborogluconat



Calcium Gluconate

Calcium Gluconate is reported as an ingredient of Calicumborogluconat in the following countries:


  • Germany

International Drug Name Search

Cefuroxime axetil Ranbaxy




Cefuroxime axetil Ranbaxy may be available in the countries listed below.


Ingredient matches for Cefuroxime axetil Ranbaxy



Cefuroxime

Cefuroxime axetil (a derivative of Cefuroxime) is reported as an ingredient of Cefuroxime axetil Ranbaxy in the following countries:


  • Germany

International Drug Name Search

Tuesday 8 September 2009

Lotronex


Lotronex is a brand name of alosetron, approved by the FDA in the following formulation(s):


LOTRONEX (alosetron hydrochloride - tablet; oral)



  • Manufacturer: PROMETHEUS LABS

    Approval date: February 9, 2000

    Strength(s): EQ 1MG BASE [RLD]


  • Manufacturer: PROMETHEUS LABS

    Approval date: December 23, 2003

    Strength(s): EQ 0.5MG BASE

Has a generic version of Lotronex been approved?


No. There is currently no therapeutically equivalent version of Lotronex available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Lotronex. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
    Patent 5,360,800
    Issued: November 1, 1994
    Inventor(s): Coates; Ian H. & North; Peter C. & Oxford; Alexander W.
    Assignee(s): Glaxo Group Limited
    The invention relates to tricyclic lactams of the general formula (I) ##STR1## wherein Im represents an imidazolyl group of the formula: ##STR2## and R.sup.1 represents a hydrogen atom or a group selected from C.sub.1-6 alkyl, C.sub.3-6 alkenyl, C.sub.3-10 alkynyl, C.sub.3-7 cycloalkyl, C.sub.3-7 cycloalkylC.sub.1-4 alkyl, phenyl, phenyl C.sub.1-3 alkyl, phenylmethoxymethyl, phenoxyethyl or phenoxymethyl, one of the groups represented by R.sup.2, R.sup.3 and R.sup.4 is a hydrogen atom or a C.sub.1-6 alkyl, C.sub.3-7 cycloalkyl, C.sub.3-6 alkenyl, phenyl or phenyl C.sub.1-3 alkyl group, and each of the other two groups, which may be the same or different, represents a hydrogen atom or a C.sub.1-6 alkhyl group; n represents 2 or 3; and physiologically acceptable salts and solvates thereof. The compounds are potent and selective antagonists of the effect of 5-HT at 5-HT.sub.3 receptors and are useful, for example, in the treatment of psychotic disorders, anxiety, and nausea and vomiting.
    Patent expiration dates:

    • January 13, 2013
      ✓ 
      Patent use: FOR WOMEN WITH SEVERE DIARRHEA-PREDOMINANT IRRITABLE BOWEL SYNDROME (IBS)
      ✓ 
      Drug substance
      ✓ 
      Drug product




  • Medicaments for the treatment of non-constipated female irritable bowel syndrome
    Patent 6,284,770
    Issued: September 4, 2001
    Inventor(s): Mangel; Allen Wayne & Northcutt; Allison Ruth
    Assignee(s): Glaxo Wellcome Inc.
    This invention relates to the use of 5-HT3 receptor antagonists in the treatment of nonconstipated female IBS patients.
    Patent expiration dates:

    • October 5, 2018
      ✓ 
      Patent use: FOR WOMEN WITH SEVERE DIARRHEA-PREDOMINANT IRRITABLE BOWEL SYNDROME (IBS)



Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • April 1, 2011 - ONCE DAILY DOSING REGIMEN FOR PATIENTS WHO BECOME CONSTIPATED ON TWICE DAILY REGIMEN

See also...

  • Lotronex Consumer Information (Drugs.com)
  • Lotronex Consumer Information (Wolters Kluwer)
  • Lotronex Consumer Information (Cerner Multum)
  • Lotronex Advanced Consumer Information (Micromedex)
  • Lotronex AHFS DI Monographs (ASHP)
  • Alosetron Consumer Information (Wolters Kluwer)
  • Alosetron Consumer Information (Cerner Multum)
  • Alosetron Advanced Consumer Information (Micromedex)
  • Alosetron Hydrochloride AHFS DI Monographs (ASHP)

Sunday 6 September 2009

Codipront




Codipront may be available in the countries listed below.


Ingredient matches for Codipront



Codeine

Codeine is reported as an ingredient of Codipront in the following countries:


  • Indonesia

Phenyltoloxamine

Phenyltoloxamine is reported as an ingredient of Codipront in the following countries:


  • Indonesia

International Drug Name Search

Saturday 5 September 2009

Tial




Tial may be available in the countries listed below.


Ingredient matches for Tial



Tramadol

Tramadol hydrochloride (a derivative of Tramadol) is reported as an ingredient of Tial in the following countries:


  • Germany

International Drug Name Search

Thursday 3 September 2009

Scripto-metic




Scripto-metic may be available in the countries listed below.


Ingredient matches for Scripto-metic



Prochlorperazine

Prochlorperazine maleate (a derivative of Prochlorperazine) is reported as an ingredient of Scripto-metic in the following countries:


  • South Africa

International Drug Name Search

Friday 28 August 2009

Esopraz




Esopraz may be available in the countries listed below.


Ingredient matches for Esopraz



Omeprazole

Omeprazole is reported as an ingredient of Esopraz in the following countries:


  • Greece

Omeprazole sodium salt (a derivative of Omeprazole) is reported as an ingredient of Esopraz in the following countries:


  • Greece

International Drug Name Search

Monday 24 August 2009

Ikestatina




Ikestatina may be available in the countries listed below.


Ingredient matches for Ikestatina



Somatostatin

Somatostatin x acetate (a derivative of Somatostatin) is reported as an ingredient of Ikestatina in the following countries:


  • Italy

  • Venezuela

International Drug Name Search

Wednesday 19 August 2009

Antiseptin




Antiseptin may be available in the countries listed below.


Ingredient matches for Antiseptin



Triclosan

Triclosan is reported as an ingredient of Antiseptin in the following countries:


  • Chile

International Drug Name Search

Tuesday 18 August 2009

dutasteride


doo-TAS-ter-ide


Commonly used brand name(s)

In the U.S.


  • Avodart

Available Dosage Forms:


  • Capsule, Liquid Filled

Therapeutic Class: Benign Prostatic Hypertrophy Agent


Pharmacologic Class: 5-Alpha Reductase Inhibitor


Uses For dutasteride


Note: Women of childbearing potential should not use or handle dutasteride capsules. Dutasteride can cause birth defects in male fetuses.


Dutasteride is used alone or in combination with tamsulosin (Flomax®) to treat men who have symptoms of an enlarged prostate gland, which is also known as benign prostatic hyperplasia (BPH). Benign enlargement of the prostate is a problem that can occur in men as they get older. The prostate gland is located below the bladder. As the prostate gland enlarges, certain muscles in the gland may become tight and get in the way of the tube that drains urine from the bladder. This can cause problems with urinating, such as a need to urinate often, a weak stream when urinating, or a feeling of not being able to empty the bladder completely.


Dutasteride blocks the action of an enzyme called 5-alpha-reductase. This enzyme changes testosterone to another hormone that causes the prostate to grow. As a result, the size of the prostate is decreased. The effect of dutasteride lasts only as long as the medicine is taken. If it is stopped, the prostate begins to grow again.


dutasteride is available only with your doctor's prescription.


Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, dutasteride is used in certain patients with the following medical conditions:


  • Male pattern alopecia.

Before Using dutasteride


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For dutasteride, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to dutasteride or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Dutasteride is not indicated for use in the pediatric population. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of dutasteride in the elderly.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersXStudies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking dutasteride, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using dutasteride with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Cimetidine

  • Ciprofloxacin

  • Diltiazem

  • Ketoconazole

  • Ritonavir

  • Verapamil

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of dutasteride. Make sure you tell your doctor if you have any other medical problems, especially:


  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of dutasteride


Take dutasteride exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.


You may take dutasteride with or without food.


Swallow the capsule whole. Do not crush, chew, or open it. The contents of the capsule may irritate your lips, mouth, or throat.


dutasteride comes with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.


Dosing


The dose of dutasteride will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of dutasteride. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (capsules):
    • For benign prostatic hyperplasia:
      • Adults—0.5 milligram (mg) once a day.

      • Children—Use is not recommended.



Missed Dose


If you miss a dose of dutasteride, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using dutasteride


It is very important that your doctor check you at regular visits to make sure that dutasteride is working properly and to check for any unwanted effects that may be caused by dutasteride.


Women and children should not use dutasteride. Pregnant women or women who may become pregnant should not handle or touch the capsules. Dutasteride can be absorbed through the skin and can cause birth defects in male fetuses. If a pregnant woman does come in contact with dutasteride, the affected area should be washed right away with soap and water, especially if the capsule is broken.


Men who have taken dutasteride should not donate blood until 6 months have passed since the last dose. Dutasteride can remain in your blood for a long time and be passed on to a pregnant woman who receives a blood transfusion.


dutasteride may increase your risk of developing high-grade prostate cancer. Tell your doctor if you have concerns about this risk.


dutasteride may affect the results of the prostate specific antigen (PSA) test, which may be used to detect prostate cancer. Make sure you tell all of your doctors that you are using dutasteride.


dutasteride does not usually affect normal sexual abilities for most men. You may notice that you ejaculate less fluid when you have sex.


dutasteride Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Rare
  • Chest pain or discomfort

  • dilated neck veins

  • extreme fatigue

  • irregular breathing

  • irregular heartbeat

  • shortness of breath

  • swelling of the face, fingers, feet, or lower legs

  • weight gain

  • wheezing

Incidence not known
  • Blistering, flaking, or peeling of the skin

  • cough

  • difficulty with swallowing

  • dizziness

  • fast heartbeat

  • hives or welts

  • itching skin

  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • redness of the skin

  • skin rash

  • tightness in the chest

  • unusual tiredness or weakness

  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • Abnormal ejaculation

  • decreased interest in sexual intercourse

  • decreased sexual performance or desire

  • impotence

  • inability to have or keep an erection

  • loss in sexual ability, desire, drive, or performance

  • pain, soreness, swelling, or discharge from the breast or breasts

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: dutasteride side effects (in more detail)



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More dutasteride resources


  • Dutasteride Side Effects (in more detail)
  • Dutasteride Use in Pregnancy & Breastfeeding
  • Dutasteride Drug Interactions
  • Dutasteride Support Group
  • 14 Reviews for Dutasteride - Add your own review/rating


  • Dutasteride Professional Patient Advice (Wolters Kluwer)

  • Dutasteride Monograph (AHFS DI)

  • Dutasteride MedFacts Consumer Leaflet (Wolters Kluwer)

  • Avodart Prescribing Information (FDA)

  • Avodart Consumer Overview



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